Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Hans-Peter Vornlocher0
Kristin K. H. Neuman0
Philipp Hadwiger0
Jonathan Miles Brown0
Date of Patent
August 3, 2021
0Patent Application Number
201802060
Date Filed
February 6, 2018
0Patent abstract
The present invention relates to methods of administering to a subject multimeric oligonucleotides having monomeric subunits joined by linkers. The multimeric oligonucleotides have a molecular weight of at least about 45 kD and other characteristics, such that their clearance due to glomerular filtration is reduced. The present invention also relates to such multimeric oligonucleotides and methods of synthesizing such multimeric oligonucleotides.
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