US Patent 11078484 Multimeric oligonucleotides having decreased kidney clearance
Patent 11078484 was granted and assigned to MPEG LA on August, 2021 by the United States Patent and Trademark Office.
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Patent abstract
The present invention relates to methods of administering to a subject multimeric oligonucleotides having monomeric subunits joined by linkers. The multimeric oligonucleotides have a molecular weight of at least about 45 kD and other characteristics, such that their clearance due to glomerular filtration is reduced. The present invention also relates to such multimeric oligonucleotides and methods of synthesizing such multimeric oligonucleotides.
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Patent Inventor Names
Hans-Peter Vornlocher0
Jonathan Miles Brown0
Kristin K. H. Neuman0
Philipp Hadwiger0
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Patent Jurisdiction
Patent Number
110784840
Date of Patent
August 3, 2021
0Patent Application Number
201802060
Date Filed
February 6, 2018
0Official Website
Patent Citations Received
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US Patent 11078484 Multimeric oligonucleotides having decreased kidney clearance
Infobox
Is a
Patent applicant
Current assignee
Patent jurisdiction
Patent number
11078484
Date of patent
August 3, 2021
Patent application number
20180206
Date Filed
February 6, 2018
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