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US Patent 11124567 Anti-TREM2 antibodies and methods of use thereof

Patent 11124567 was granted and assigned to Denali Therapeutics on September, 2021 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Patent Applicant
Denali Therapeutics
Denali Therapeutics
Current Assignee
Denali Therapeutics
Denali Therapeutics
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
11124567
Date of Patent
September 21, 2021
Patent Application Number
20210115
Date Filed
January 15, 2021
Patent Citations Received
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US Patent 11643446 Progranulin variants
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Patent abstract

In one aspect, antibodies that specifically bind to a human triggering receptor expressed on myeloid cells 2 (TREM2) protein are provided. In some embodiments, the antibody decreases levels of soluble TREM2 (sTREM2). In some embodiments, the antibody enhances TREM2 activity.

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