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US Patent 11168138 Anti-PDL1, IL-15 and TGF-beta receptor combination molecules

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Patent Citations Received
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US Patent 11992516 Compositions comprising IL-15-based molecules and immune checkpoint inhibitor antibodies
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US Patent 11975059 IL-15-based fusions to IL-12 and IL-18
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US Patent 11925676 Method for treating neoplasia with an anti-CD38 antibody and an IL-15:IL-15R complex
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US Patent 11890323 Method of treating cancer with composition comprising IL-15-based molecules and BCG
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US Patent 11872272 IL-15-based fusions to IL-12 and IL-18
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Patent abstract

The invention features multi-specific protein complexes with one domain comprising IL-15 or a functional variant, a cytokine receptor or cytokine ligand, and a binding domain specific to a disease antigen, immune checkpoint or signaling molecule.

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Patent Inventor Names
Hing C. Wong0
Qiongzhen Li0
Xiaoyun Zhu0
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Official Website
https://pdfpiw.uspto.gov/.piw?Docid=111681380
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Infobox
Is a
Patent
Patent
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Patent Applicant
Altor BioScience
Altor BioScience
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
111681380
Date of Patent
November 9, 2021
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Patent Application Number
201903260
Date Filed
March 26, 2019
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Official Website
https://pdfpiw.uspto.gov/.piw?Docid=111681380
Patent Citations Received
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US Patent 11498950 Fusion molecules and IL-15 variants
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Patent Primary Examiner
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Bridget E Bunner
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Patent Citations Received
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US Patent 11498950 Fusion molecules and IL-15 variants
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Website URL
https://pdfpiw.uspto.gov/.piw?Docid=11168138
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 US Patent 11168138 Anti-PDL1, IL-15 and TGF-beta receptor combination molecules

Infobox
Is a
Patent
Patent
Patent applicant
Altor BioScience
Altor BioScience
Patent jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent number
11168138
Date of patent
November 9, 2021
Patent application number
20190326
Date Filed
March 26, 2019
Patent primary examiner
‌
Bridget E Bunner

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