US Patent 11174487 Stable genomic integration of multiple polynucleotide copies
Patent 11174487 was granted and assigned to Novozymes A/S on November, 2021 by the United States Patent and Trademark Office.
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Patent abstract
Methods of constructing a cell comprising in its chromosome one or more copies of an open reading frame (ORF) or operon encoding at least one polypeptide of interest, each copy being under the transcriptional control of a heterologous promoter using a site specific recombinase and in vivo integration by recombination; resulting cells, and methods for producing a polypeptide of interest using the resulting cells.
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Patent Inventor Names
Anne Breuner0
Michael Dolberg Rasmussen0
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US Patent 11174487 Stable genomic integration of multiple polynucleotide copies
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Patent applicant
Current assignee
Patent jurisdiction
Patent number
11174487
Date of patent
November 16, 2021
Patent application number
15481879
Date Filed
April 7, 2017
Patent primary examiner
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