Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
November 23, 2021
Patent Application Number
16043950
Date Filed
July 24, 2018
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides methods for analyzing polynucleotides such as genomic DNA. In some embodiments, the disclosure provides a method for preparing and amplifying a genomic DNA library in situ in a fixed biological sample. The method comprises treating a fixed biological sample with an insertional enzyme complex to produce tagged fragments of genomic DNA. The method further comprises circularizing the tagged fragments of genomic DNA. The method further comprises amplifying the tagged fragments of genomic DNA.
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