Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Edward Stuart Boyden
Yongxin Zhao
Pablo Valdes Quevedo
Date of Patent
October 31, 2023
Patent Application Number
17111135
Date Filed
December 3, 2020
Patent Citations
...
Patent Primary Examiner
Patent abstract
The invention provides a method for preparing an expanded biological specimen suitable for microscopic analysis. Expanding the biological sample can be achieved by anchoring biomolecules to a polymer network and swelling, or expanding, the polymer network, thereby moving the biomolecules apart as further described below. As the biomolecules are anchored to the polymer network isotropic expansion of the polymer network retains the spatial orientation of the biomolecules resulting in an expanded, or enlarged, biological specimen.
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