Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
December 28, 2021
Patent Application Number
16838395
Date Filed
April 2, 2020
Patent Citations Received
Patent Primary Examiner
Patent abstract
Disclosed is an isolated or purified T cell receptor (TCR) having antigenic specificity for mutated Kirsten rat sarcoma viral oncogene homolog (KRAS) presented in the context of an HLA-Cw*0802 molecule. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal.
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