Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
February 1, 2022
Patent Application Number
16942599
Date Filed
July 29, 2020
Patent Citations
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides engineered RNA polymerase variants and compositions comprising these variants. The present invention further provides engineered T7 RNA polymerase variants and compositions comprising these variants. These variants have been evolved for selective incorporation of the m7G(5′)ppp(5′)m7G cap analog over GTP at the initiation of in vitro transcription. The present invention also provides methods for selective capping of RNA transcripts.
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