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US Patent 11285207 Bispecific antibodies specifically binding to PD1 and LAG3

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Sabine Imhof-Jung0

Stefan Seeber0

Jens Fischer0

Laura Codarri Deak0

Patrick Alexander Aaron Weber0

Christian Klein0

Date of Patent

March 29, 2022

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Patent Application Number

159443940

Date Filed

April 3, 2018

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Patent Citations

US Patent 10344089 Human antibodies that bind lymphocyte activation gene-3 (LAG-3), and uses thereof

US Patent 10392445 Tumor necrosis factor (TNF) family ligand trimer-containing antigen-binding molecules

US Patent 10562903 Bridged piperidine derivatives

US Patent 10718762 Cellular based fret assay for the determination of simultaneous binding

US Patent 10596173 Combination therapy of an HBV capsid assembly inhibitor and an interferon

US Patent 10934352 Bi-specific antibodies against Tim-3 and PD-1 for immunotherapy in chronic immune conditions

US Patent 10761097 Method for the detection of a binding partner of a multispecific binder

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US Patent 10287352 Bispecific antibodies specific for PD1 and TIM3

Patent Citations Received

US Patent 11608376 Tumor-targeted agonistic CD28 antigen binding molecules

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US Patent 12023368 Immunoconjugates

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US Patent 12060435 Multi-specific ligand binders

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US Patent 12065478 HER2-targeting antigen binding molecules comprising 4-1BBL

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Patent Primary Examiner

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CPC Code

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The invention relates to bispecific antibodies comprising a first antigen binding domain that specifically binds to PD1 and a second antigen binding domain that specifically binds to LAG3. The invention further relates to methods of producing these molecules and to methods of using the same.

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