Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Vladimir Presnyak0
Ailin Bai0
Ellalahewage Sathyajith Kumarasinghe0
Iain McFadyen0
Joshua P. Frederick0
Kerry Benenato0
Stephen G. Hoge0
Susannah Hewitt0
Date of Patent
May 31, 2022
0Patent Application Number
173529040
Date Filed
June 21, 2021
0Patent Citations
Patent Citations Received
Patent Primary Examiner
The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of combinations of immunomodulatory polynucleotides (e.g., mRNAs) encoding an immune response primer polypeptide (e.g., an interleukin 23 (IL-23) polypeptide or an interleukin 36γ (IL-36-gamma) polypeptide), and an immune response co-stimulatory signal polypeptide (e.g., an OX40L polypeptide).
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