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US Patent 11345899 Variant forms of urate oxidase and use thereof

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Simona Mendelovitz0

Jacob Hartman0

Date of Patent

May 31, 2022

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Patent Application Number

169110740

Date Filed

June 24, 2020

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Patent Citations

US Patent 10823727 Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during pegylated uricase therapy

US Patent 10731139 Variant forms of urate oxidase and use thereof

US Patent 10160958 Variant forms of urate oxidase and use thereof

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Patent Citations Received

US Patent 11598767 Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during pegylated uricase therapy

US Patent 11639927 Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during PEGylated uricase therapy

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US Patent 11781119 Variant forms of urate oxidase and use thereof

US Patent 11982670 Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during pegylated uricase therapy

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US Patent 12121566 Methods for treating gout

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Patent Primary Examiner

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CPC Code

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Genetically modified proteins with uricolytic activity are described. Proteins comprising truncated urate oxidases and methods for producing them, including PEGylated proteins comprising truncated urate oxidase are described.

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