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US Patent 11781119 Variant forms of urate oxidase and use thereof

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Is a

Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Patent Inventor Names

Jacob Hartman

Simona Mendelovitz

Date of Patent

October 10, 2023

Patent Application Number

17724091

Date Filed

April 19, 2022

Patent Citations

US Patent 7964381 Variant form of urate oxidase and use thereof

US Patent 9402827 Treatment of gout

US Patent 9534013 Purification of proteins with cationic surfactant

US Patent 9670467 Variant forms of urate oxidase and use thereof

US Patent 9885024 PEG-urate oxidase conjugates and use thereof

US Patent 9926537 Variant forms of urate oxidase and use thereof

US Patent 9926538 Variant forms of urate oxidase and use thereof

US Patent 10139399 Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during PEGylated uricase therapy

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Patent Citations Received

US Patent 12121566 Methods for treating gout

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US Patent 11982670 Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during pegylated uricase therapy

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Patent Primary Examiner

CPC Code

Patent abstract

Genetically modified proteins with uricolytic activity are described. Proteins comprising truncated urate oxidases and methods for producing them, including PEGylated proteins comprising truncated urate oxidase are described.

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