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US Patent 9926538 Variant forms of urate oxidase and use thereof

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Jacob Hartman0

Simona Mendelovitz0

Date of Patent

March 27, 2018

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Patent Application Number

156494880

Date Filed

July 13, 2017

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Patent Citations Received

US Patent 11781119 Variant forms of urate oxidase and use thereof

US Patent 12121566 Methods for treating gout

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US Patent 11982670 Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during pegylated uricase therapy

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Patent Primary Examiner

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Patent abstract

Genetically modified proteins with uricolytic activity are described. Proteins comprising truncated urate oxidases and methods for producing them, including PEGylated proteins comprising truncated urate oxidase are described.

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