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US Patent 11781119 Variant forms of urate oxidase and use thereof

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US Patent 12121566 Methods for treating gout
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 US Patent 11781119 Variant forms of urate oxidase and use thereof

Article

Patent abstract

Genetically modified proteins with uricolytic activity are described. Proteins comprising truncated urate oxidases and methods for producing them, including PEGylated proteins comprising truncated urate oxidase are described.

Infobox
Is a
Patent
Patent
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
11781119
Patent Inventor Names
Jacob Hartman
Simona Mendelovitz
Date of Patent
October 10, 2023
Patent Application Number
17724091
Date Filed
April 19, 2022
Patent Citations
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US Patent 7723089 PEG-urate oxidase conjugates and use thereof
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US Patent 7811800 Variant form of urate oxidase and use thereof
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US Patent 7927589 PEG-urate oxidase conjugates and use thereof
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US Patent 7927852 Aggregate-free urate oxidase for preparation of non-immunogenic polymer conjugates
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US Patent 7964381 Variant form of urate oxidase and use thereof
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US Patent 8034594 Variant form of urate oxidase and use thereof
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US Patent 8067553 PEG-urate oxidase conjugates and use thereof
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US Patent 8148123 Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
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US Patent 8178334 Variant form of urate oxidase and use thereof
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US Patent 8188224 Variant forms of urate oxidase and use thereof
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US Patent 8293228 Variant form of urate oxidase and use thereof
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US Patent 8465735 Variant form of urate oxidase and use thereof
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US Patent 8541205 Variant forms of urate oxidase and use thereof
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US Patent 8618267 PEG-urate oxidase conjugates and use thereof
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US Patent 8913915 Charging device
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US Patent 8921064 Method for purifying urate oxidase tetramers and octamers
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US Patent 9017980 Variant forms of urate oxidase and use thereof
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US Patent 9377454 Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during pegylated uricase therapy
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US Patent 9402827 Treatment of gout
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US Patent 9534013 Purification of proteins with cationic surfactant
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US Patent 9670467 Variant forms of urate oxidase and use thereof
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US Patent 9885024 PEG-urate oxidase conjugates and use thereof
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US Patent 9926537 Variant forms of urate oxidase and use thereof
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US Patent 9926538 Variant forms of urate oxidase and use thereof
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US Patent 10139399 Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during PEGylated uricase therapy
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US Patent 10160958 Variant forms of urate oxidase and use thereof
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US Patent 10731139 Variant forms of urate oxidase and use thereof
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US Patent 10823727 Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during pegylated uricase therapy
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US Patent 11345899 Variant forms of urate oxidase and use thereof
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US Patent 11598767 Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during pegylated uricase therapy
Patent Primary Examiner
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Julie Ha
CPC Code
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C12Y 107/03003
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C12N 9/0046
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C12N 9/0048
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A61K 47/60
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A61K 38/44

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