Is a
Patent attributes
Patent Applicant
Patent Jurisdiction
Patent Number
Patent Inventor Names
Aris N. Economides0
Christopher Schoenherr0
Sarah J. Hatsell0
Vincent J. Idone0
Date of Patent
August 23, 2022
0Patent Application Number
164390680
Date Filed
June 12, 2019
0Patent Citations Received
Patent Primary Examiner
A genetically modified rodent is provided that comprises a modified Acvr1 gene that comprises a conditional altered exon 7 encoding R258G in anti sense orientation, flanked by site-specific recombinase recognition sites, wherein the altered exon is inverted to sense orientation upon action of a recombinase, resulting in ectopic bone formation.
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