Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Sarah J. Hatsell0
Aris N. Economides0
Vincent J. Idone0
Christopher Schoenherr0
Date of Patent
September 17, 2024
0Patent Application Number
178110890
Date Filed
July 7, 2022
0Patent Citations
Patent Primary Examiner
Patent abstract
A genetically modified rodent is provided that comprises a modified Acvr1 gene that comprises a conditional altered exon 7 encoding R258G in antisense orientation, flanked by site-specific recombinase recognition sites, wherein the altered exon is inverted to sense orientation upon action of a recombinase, resulting in ectopic bone formation.
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