US Patent 11492408 Bi-specific T-cell engager specific for BCMA
Patent 11492408 was granted and assigned to UCL Business Ltd on November, 2022 by the United States Patent and Trademark Office.
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Kwee Yong0
Lydia Lee0
Martin Pulé0
Neil Chaplin0
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US Patent 11492408 Bi-specific T-cell engager specific for BCMA
Article
The present invention provides a bi-specific molecule which comprises: (i) a first domain which binds B cell maturation antigen (BCMA) and comprises at least part of a proliferation-inducing ligand (APRIL); and (ii) a second domain capable of activating a T cell. The invention also provides the use of such a molecule in the treatment of plasma-cell mediated diseases, such as multiple myeloma.
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Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
114924080
Date of Patent
November 8, 2022
0Patent Application Number
150281130
Date Filed
October 10, 2014
0Patent Citations
Patent Primary Examiner
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