US Patent 11505590 T cell receptors
Patent 11505590 was granted and assigned to Immunocore on November, 2022 by the United States Patent and Trademark Office.
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Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
115055900
Date of Patent
November 22, 2022
0Patent Application Number
160921740
Date Filed
April 7, 2017
0Patent Primary Examiner
Edits on 25 Nov, 2022
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US Patent 11505590 T cell receptors
Article
The present invention relates to T cell receptors (TCRs) that bind the HLA-A*02 restricted peptide GVYDGREHTV (SEQ ID NO: 1) derived from the germline cancer antigen MAGE A4. Said TCRs may comprise non-natural mutations within the alpha and/or beta variable domains relative to a native MAGE A4 TCR. The TCRs of the invention are particularly suitable for use as novel immunotherapeutic reagents for the treatment of malignant disease.
Infobox
Is a
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
115055900
Date of Patent
November 22, 2022
0Patent Application Number
160921740
Date Filed
April 7, 2017
0Patent Primary Examiner
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