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Patent Applicant
Patent Jurisdiction
Patent Number
Date of Patent
December 6, 2022
Patent Application Number
16358395
Date Filed
March 19, 2019
Patent Citations
Patent Primary Examiner
Non-human animal cells and non-human animals comprising CRISPR/Cas synergistic activation mediator system components and methods of making and using such non-human animal cells and non-human animals are provided. Methods are provided for using such non-human animals to increase expression of target genes in vivo and to assess CRISPR/Cas synergistic activation mediator systems for the ability to increase expression of target genes in vivo.
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