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US Patent 11679144 IL-15-based molecules and methods of use thereof

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Is a

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Date of Patent

June 20, 2023

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Patent Application Number

178259590

Date Filed

May 26, 2022

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Patent Citations

US Patent 8163879 Fusion molecules and IL-15 variants

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US Patent 8492118 Fusion molecules and IL-15 variants

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US Patent 8940288 Method for treating cancer by administering IL-15 and IL-15Ralpha complexes

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US Patent 8940289 Fusion molecules and IL-15 variants

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US Patent 9255141 Multimeric IL-15 soluble fusion molecules and methods of treating neoplasia and HIV using same

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US Patent 9365630 Compositions and methods for Immunomodulation in an organism

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US Patent 9428573 Multimeric IL-15 soluble fusion molecules and methods of making and using same

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US Patent 9464127 Fusion molecules and IL-15 variants

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Patent Primary Examiner

Bridget E Bunner

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The invention features combination therapies using an IL-15-based superagonist complex and an antibody to effectively treat subjects with cancer and infectious diseases.

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