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US Patent 11679144 IL-15-based molecules and methods of use thereof

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 US Patent 11679144 IL-15-based molecules and methods of use thereof

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The invention features combination therapies using an IL-15-based superagonist complex and an antibody to effectively treat subjects with cancer and infectious diseases.

Infobox
Is a
Patent
Patent
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
116791440
Date of Patent
June 20, 2023
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Patent Application Number
178259590
Date Filed
May 26, 2022
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Patent Citations
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US Patent 11104716 Multimeric IL-15 soluble fusion molecules and methods of making and using same
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US Patent 7112660 Modified cytokine
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US Patent 11173191 IL-15-based molecules and methods of use thereof
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US Patent 8124084 Compositions and methods for immunomodulation in an organism using IL-15 and soluble IL-15Ra
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US Patent 8163879 Fusion molecules and IL-15 variants
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US Patent 8492118 Fusion molecules and IL-15 variants
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US Patent 8940288 Method for treating cancer by administering IL-15 and IL-15Ralpha complexes
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US Patent 8940289 Fusion molecules and IL-15 variants
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US Patent 9255141 Multimeric IL-15 soluble fusion molecules and methods of treating neoplasia and HIV using same
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US Patent 9365630 Compositions and methods for Immunomodulation in an organism
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US Patent 9428573 Multimeric IL-15 soluble fusion molecules and methods of making and using same
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US Patent 9464127 Fusion molecules and IL-15 variants
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US Patent 9593152 Methods of treating disease with fusion molecules comprising IL-15 variants
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US Patent 10150805 Multimeric IL-15 soluble fusion molecules and methods of making and using same
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US Patent 10358478 Multimeric IL-15 soluble fusion molecules and methods of making and using same
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US Patent 10450359 IL-15 variants and uses thereof
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US Patent 10537615 IL-15-based molecules and methods of use thereof
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US Patent 10865230 Construction and characterization of multimeric IL-15-based molecules with CD3 binding domains
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US Patent 10899821 Method of treating neoplasia with a multimeric IL-15 soluble fusion molecule
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US Patent 11046747 Multimeric IL-15 soluble fusion molecules and methods of making and using same
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US Patent 11053299 Superkine
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Patent Primary Examiner
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Bridget E Bunner
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