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US Patent 11053299 Superkine

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Is a

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Hing C. Wong0

Kai-Ping Han0

Peter Rhode0

Xiaoyun Zhu0

Bai Liu0

Patrick Soon-Shiong0

Date of Patent

July 6, 2021

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Patent Application Number

164422650

Date Filed

June 14, 2019

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Patent Citations

US Patent 10150805 Multimeric IL-15 soluble fusion molecules and methods of making and using same

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US Patent 10537615 IL-15-based molecules and methods of use thereof

US Patent 10450359 IL-15 variants and uses thereof

US Patent 10358478 Multimeric IL-15 soluble fusion molecules and methods of making and using same

Patent Citations Received

US Patent 11992516 Compositions comprising IL-15-based molecules and immune checkpoint inhibitor antibodies

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US Patent 11673932 Fusion molecules and IL-15 variants

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US Patent 11679144 IL-15-based molecules and methods of use thereof

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US Patent 11318201 Multimeric IL-15-based molecules

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US Patent 11369679 Multimeric IL-15-based molecules

US Patent 11890323 Method of treating cancer with composition comprising IL-15-based molecules and BCG

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US Patent 11925676 Method for treating neoplasia with an anti-CD38 antibody and an IL-15:IL-15R complex

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US Patent 11471511 IL-15-based molecules and methods of use thereof

Patent Primary Examiner

0

Patent abstract

Contemplated compositions and methods comprise chimeric molecule complexes that advantageously provide activating signaling to immune competent cells when bound to ALL cells. Furthermore, chimeric molecule complexes include an Fc portion to extend serum half live time and facilitate purification.

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