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US Patent 11471511 IL-15-based molecules and methods of use thereof

Overview Structured Data Issues Contributors Activity

Is a

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Patent attributes

Patent Applicant

Altor BioScience

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Wenxin Xu0

Hing C. Wong0

Peter Rhode0

Bai Liu0

Date of Patent

October 18, 2022

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Patent Application Number

169251380

Date Filed

July 9, 2020

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Patent Citations

US Patent 10865230 Construction and characterization of multimeric IL-15-based molecules with CD3 binding domains

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US Patent 11053299 Superkine

US Patent 11046747 Multimeric IL-15 soluble fusion molecules and methods of making and using same

US Patent 10150805 Multimeric IL-15 soluble fusion molecules and methods of making and using same

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US Patent 10358478 Multimeric IL-15 soluble fusion molecules and methods of making and using same

US Patent 10450359 IL-15 variants and uses thereof

US Patent 10537615 IL-15-based molecules and methods of use thereof

Patent Citations Received

US Patent 11992516 Compositions comprising IL-15-based molecules and immune checkpoint inhibitor antibodies

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US Patent 11673932 Fusion molecules and IL-15 variants

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US Patent 11890323 Method of treating cancer with composition comprising IL-15-based molecules and BCG

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US Patent 11925676 Method for treating neoplasia with an anti-CD38 antibody and an IL-15:IL-15R complex

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Patent Primary Examiner

Elizabeth C. Kemmerer

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The invention features combination therapies using an IL-15-based superagonist complex and an antibody to effectively treat subjects with cancer and infectious diseases.

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