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US Patent 11053299 Superkine

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US Patent 11992516 Compositions comprising IL-15-based molecules and immune checkpoint inhibitor antibodies
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US Patent 11925676 Method for treating neoplasia with an anti-CD38 antibody and an IL-15:IL-15R complex
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US Patent 11890323 Method of treating cancer with composition comprising IL-15-based molecules and BCG
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Patent abstract

Contemplated compositions and methods comprise chimeric molecule complexes that advantageously provide activating signaling to immune competent cells when bound to ALL cells. Furthermore, chimeric molecule complexes include an Fc portion to extend serum half live time and facilitate purification.

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Patent Inventor Names
Bai Liu0
Hing C. Wong0
Kai-Ping Han0
Patrick Soon-Shiong0
Peter Rhode0
Xiaoyun Zhu0
Edits on 21 Jun, 2023
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US Patent 11679144 IL-15-based molecules and methods of use thereof
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US Patent 11673932 Fusion molecules and IL-15 variants
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edited on 20 May, 2023
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Official Website
https://pdfpiw.uspto.gov/.piw?Docid=110532990
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Infobox
Is a
Patent
Patent
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
110532990
Date of Patent
July 6, 2021
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Patent Application Number
164422650
Date Filed
June 14, 2019
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Official Website
https://pdfpiw.uspto.gov/.piw?Docid=110532990
Patent Citations
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US Patent 10150805 Multimeric IL-15 soluble fusion molecules and methods of making and using same
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US Patent 10358478 Multimeric IL-15 soluble fusion molecules and methods of making and using same
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US Patent 10450359 IL-15 variants and uses thereof
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US Patent 10537615 IL-15-based molecules and methods of use thereof
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Patent Citations Received
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US Patent 11318201 Multimeric IL-15-based molecules
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US Patent 11369679 Multimeric IL-15-based molecules
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US Patent 11471511 IL-15-based molecules and methods of use thereof
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Patent Primary Examiner
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Prema M Mertz
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edited on 22 Apr, 2023
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US Patent 11471511 IL-15-based molecules and methods of use thereof
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edited on 29 Jun, 2022
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Patent citations received
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US Patent 11369679 Multimeric IL-15-based molecules
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Website URL
https://pdfpiw.uspto.gov/.piw?Docid=11053299
Edits on 19 May, 2022
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edited on 19 May, 2022
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Patent citations received
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US Patent 11318201 Multimeric IL-15-based molecules
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