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US Patent 9593152 Methods of treating disease with fusion molecules comprising IL-15 variants

Patent 9593152 was granted and assigned to Altor BioScience on March, 2017 by the United States Patent and Trademark Office.

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Is a

Patent attributes

Patent Applicant

Altor BioScience

Current Assignee

Altor BioScience

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Patent Inventor Names

Kai-ping Han0

Peter Rhode0

Hing C. Wong0

Xiaoyun Zhu0

Date of Patent

March 14, 2017

Patent Application Number

14568573

Date Filed

December 12, 2014

Patent Citations Received

US Patent 11992516 Compositions comprising IL-15-based molecules and immune checkpoint inhibitor antibodies

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US Patent 11673932 Fusion molecules and IL-15 variants

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US Patent 11679144 IL-15-based molecules and methods of use thereof

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US Patent 11890323 Method of treating cancer with composition comprising IL-15-based molecules and BCG

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US Patent 11925676 Method for treating neoplasia with an anti-CD38 antibody and an IL-15:IL-15R complex

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Patent Primary Examiner

Patent abstract

The instant invention provides soluble fusion protein complexes and IL-15 variants that have therapeutic and diagnostic use, and methods for making such proteins. The instant invention additionally provides methods of stimulating or suppressing immune responses in a mammal using the fusion protein complexes and IL-15 variants of the invention.

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