Is a
Patent attributes
Patent Applicant
Patent Jurisdiction
Patent Number
Date of Patent
June 27, 2023
0Patent Application Number
166731190
Date Filed
November 4, 2019
0Patent Citations
Patent Primary Examiner
Non-human animals, and methods and compositions for making and using the same, are provided, wherein the non-human animals comprise a humanization of a Programmed cell death 1 (Pdcd1) gene. The non-human animals, in some embodiments, comprise a genetic modification to an endogenous Pdcd1 gene so that the non-human animals express a PD-1 polypeptide that includes a human portion and an endogenous portion (e.g., a non-human portion).
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