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US Patent 11712446 Methods of mobilizing marrow infiltrating lymphocytes and uses thereof

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 US Patent 11712446 Methods of mobilizing marrow infiltrating lymphocytes and uses thereof

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Methods are disclosed for the mobilization of marrow infiltrating cells (MILs) using E-selectin antagonists for the treatment of disorders such as cancer. Methods for treating or preventing cancers using MILs mobilized by E-selectin antagonists are further disclosed.

Infobox
Is a
Patent
Patent
0
Patent Applicant
GlycoMimetics
GlycoMimetics
0
Current Assignee
GlycoMimetics
GlycoMimetics
0
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
117124460
Date of Patent
August 1, 2023
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Patent Application Number
167676980
Date Filed
November 29, 2018
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Patent Citations
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US Patent 7087212 Multicomponent assemblies having enhanced binding properties for diagnosis and therapy
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US Patent 7390784 Administering bifunctional molecules containing a drug moiety and presenter protein ligand for therapy
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US Patent 7414065 Methods to modulate conditions mediated by the CXCR4 receptor
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US Patent 8039442 Compounds and methods for treatment of sickle cell disease or complications associated therewith
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US Patent 8258290 Glycomimetic inhibitors of the PA-IL lectin, PA-IIL lectin or both the lectins from
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US Patent 8410066 Heterobifunctional inhibitors of E-selectins and CXCR4 chemokine receptors
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US Patent 11197877 Galactopyranosyl-cyclohexyl derivauves as E-selectin antagonists
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US Patent 8633303 Heterobifunctional pan-selectin inhibitors
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US Patent RE44778 Heterobifunctional pan-selectin inhibitors
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US Patent 8895510 Pan-selectin inhibitor with enhanced pharmacokinetic activity
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US Patent 8921328 E-selectin antagonists
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US Patent 9109002 E-selectin antagonist compounds, compositions, and methods of use
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US Patent 9254322 Compositions comprising E-selectin antagonists and uses therefor
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US Patent 9486497 Treatment of immunocompromised conditions
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US Patent 9534009 Pan-selectin inhibitor with enhanced pharmacokinetic activity
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US Patent 9796745 E-selectin antagonist compounds, compositions, and methods of use
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US Patent 9867841 Compounds, compositions and methods using E-selectin antagonists for mobilization of hematopoietic cells
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US Patent 11072625 Highly potent multimeric e-selectin antagonists
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Patent Primary Examiner
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My-Chau T. Tran
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