US Patent 11760999 RAAV-based compositions and methods for treating amyotrophic lateral sclerosis

Is a

Patent

Patent attributes

Patent Applicant

University of Massachusetts

Current Assignee

University of Massachusetts

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

11760999

Patent Inventor Names

Robert H. Brown, Jr.

Christian Mueller

Date of Patent

September 19, 2023

Patent Application Number

17174452

Date Filed

February 12, 2021

Patent Citations

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US Patent 7456015 Tetracycline-regulated adeno-associated viral (AAV) vectors for gene delivery to the nervous system

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US Patent 7498316 Methods and compositions for treating gain-of-function disorders using RNA interference

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US Patent 7622455 Methods for slowing familial ALS disease progression

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US Patent 7678895 Antisense modulation of superoxide dismutase 1, soluble expression

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US Patent 7691995 In vivo production of small interfering RNAS that mediate gene silencing

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US Patent 7750144 Methods and compositions for enhancing the efficacy and specificity of RNA silencing

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US Patent 7772203 Methods and compositions for controlling efficacy of RNA silencing

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US Patent 7892793 Allele-specific RNA interference

...

Patent Primary Examiner

‌

Kimberly Chong

Patent abstract

The invention relates to inhibitory nucleic acids and rAAV-based compositions, methods and kits useful for treating Amyotrophic Lateral Sclerosis.

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US Patent 11760999 RAAV-based compositions and methods for treating amyotrophic lateral sclerosis

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