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US Patent 11801306 Compositions and methods for targeted RNA delivery

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Is a

Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Patent Inventor Names

Lisa N. Kasiewicz

Caroline Reiss

Padma Malyala

Kallanthottathil G. Rajeev

Alexandra Chadwick

Souvik Biswas

Date of Patent

October 31, 2023

Patent Application Number

17533461

Date Filed

November 23, 2021

Patent Citations

US Patent 10358643 Poly oligomer compound with biocleavable conjugates

US Patent 9879265 Oligonucleotide conjugates

US Patent 8106022 Carbohydrate conjugates as delivery agents for oligonucleotides

Patent Primary Examiner

Genevieve S Alley

CPC Code

Patent abstract

Provided herein are compositions, methods of making the same, and methods for targeted delivery of therapeutic agents for modifying expression and function of target genes, e.g. proteins involved in lipid and cholesterol metabolism such as PCSK9. Further provided herein are compositions and methods of treating conditions related to coronary disease.

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