Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Annick Goergler
Philipp Schmid
Fabian Dey
Eric Andre Kusznir
Roger Norcross
Date of Patent
October 31, 2023
Patent Application Number
16809336
Date Filed
March 4, 2020
Patent Citations
...
Patent Citations Received
0
Patent Primary Examiner
Patent abstract
The present invention provides selected glutarimides which bind to the ubiquitously expressed E3 ligase protein cereblon (CRBN) and alter the substrate specificity of the CRBN E3 ubiquitin ligase complex, resulting in breakdown of intrinsic downstream proteins. The disclosed compounds are useful for the treatment of cancer.
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