US Patent 11833157 Precipitation resistant small molecule drug formulations
Patent 11833157 was granted and assigned to Xeris Pharmaceuticals, Inc. on December, 2023 by the United States Patent and Trademark Office.
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US Patent 11833157 Precipitation resistant small molecule drug formulations
Article
Patent abstract
Embodiments of the invention are directed to formulations that provide a solution to the problem of small molecule (e.g., diazepam) precipitation at the injection site when administered as a highly-concentrated formulation. In certain aspects the formulations include at least one surfactant in a non-aqueous formulation, which prevents small molecule precipitation and improves the bioavailability of the drug by enhancing absorption into the systemic circulation.
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Patent Applicant
Current Assignee
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Patent Number
Patent Inventor Names
Brian R. Sloat0
Michael A. Sandoval0
Steven J. Prestrelski0
Date of Patent
December 5, 2023
0Patent Application Number
173193710
Date Filed
May 13, 2021
0Patent Citations
Patent Primary Examiner
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