Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Ulrich Baxa0
John Mascola0
Aliaksandr Druz0
Mallika Sastry0
Ivelin Stefanov Georgiev0
Man Chen0
Joseph Van Galen0
Cinque Soto0
...
Date of Patent
January 23, 2024
0Patent Application Number
175243800
Date Filed
November 11, 2021
0Patent Citations
Patent Primary Examiner
Patent abstract
Embodiments of a recombinant Respiratory Syncytial Virus (RSV) F ectodomain trimer stabilized in a prefusion conformation are provided. Also disclosed are nucleic acids encoding the RSV F ectodomain trimer and methods of producing the RSV F ectodomain trimer. Methods for inducing an immune response in a subject are also disclosed. In some embodiments, the method can be a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the recombinant RSV F ectodomain trimer to the subject.
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