Patent attributes
A processor-implemented method for closed-loop control in steady-state conditions includes determining, based on data including historical bolus information but excluding historical basal information, an amount of unmetabolized therapeutic substance in a patient; determining, based on a difference between a most recent measurement of a physiological condition of the patient and a target value for the physiological condition, a first amount or rate of a basal dosage for delivery to the patient; adjusting, based on the amount of unmetabolized therapeutic substance, the first amount or rate of the basal dosage to determine a second amount or rate of the basal dosage; and causing delivery of the second amount or rate of the basal dosage based on communicating the second amount or rate in a delivery command.
