US Patent 11919954 Anti-TREM-1 antibodies and uses thereof
Patent 11919954 was granted and assigned to Bristol-Myers Squibb Company on March, 2024 by the United States Patent and Trademark Office.
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US Patent 11919954 Anti-TREM-1 antibodies and uses thereof
Article
Patent abstract
Provided herein are antibodies, or antigen-binding portions thereof, that specifically bind and inhibit TREM-1 signaling, wherein the antibodies do not bind to one or more FcγRs and do not induce the myeloid cells to produce inflammatory cytokines. Also provided are uses of such antibodies, or antigen-binding portions thereof, in therapeutic applications, such as treatment of autoimmune diseases.
Infobox
Is a
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Aaron P. Yamniuk0
Achal Pashine0
Derek A. Holmes0
Guodong Chen0
Michael L. Gosselin0
Priyanka Apurva Madia0
Richard Yu-Cheng Huang0
Stephen Michael Carl0
Date of Patent
March 5, 2024
0Patent Application Number
174723020
Date Filed
September 10, 2021
0Patent Citations
Patent Primary Examiner
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