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US Patent 11920133 RAAV-based compositions and methods

Patent 11920133 was granted and assigned to University of Massachusetts on March, 2024 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

University of Massachusetts

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Current Assignee

University of Massachusetts

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Christian Mueller0

Terence Flotte0

Phillip D. Zamore0

Date of Patent

March 5, 2024

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Patent Application Number

175761300

Date Filed

January 14, 2022

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Patent Citations

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US Patent 7022519 Compositions and methods for helper-free production of recombinant adeno-associated viruses

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US Patent 7235393 Method for direct rescue and amplification of integrated viruses from cellular DNA of tissues

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US Patent 10077452 rAAV-based compositions and methods

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US Patent 10166297 Isolation of novel AAV's and uses thereof

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US Patent 10300146 Isolation of novel AAV's and uses thereof

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US Patent 10597656 RAAV-based compositions and methods

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Patent Primary Examiner

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CPC Code

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Patent abstract

The invention relates to isolated nucleic acids and rAAV-based compositions, methods and kits useful for treating genetic diseases (e.g., alpha-1 antitrypsin deficiency).

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