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US Patent 11926817 Microfluidic apparatus and methods of use thereof

Patent 11926817 was granted and assigned to Nutcracker Therapeutics, Inc. on March, 2024 by the United States Patent and Trademark Office.

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 US Patent 11926817 Microfluidic apparatus and methods of use thereof

Article

Patent abstract

Apparatuses and methods are described herein for processing polynucleotides in a sealed path environment. The apparatuses include optical sensors to monitor operations and to track material usage for good manufacturing practice.

Infobox
Is a
Patent
Patent
0
Patent Applicant
Nutcracker Therapeutics, Inc.
Nutcracker Therapeutics, Inc.
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Current Assignee
Nutcracker Therapeutics, Inc.
Nutcracker Therapeutics, Inc.
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
119268170
Patent Inventor Names
Benjamin Eldridge0
Ximiao Wen0
Date of Patent
March 12, 2024
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Patent Application Number
169898240
Date Filed
August 10, 2020
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Patent Citations
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US Patent 7118883 Process for producing peptides by using in vitro transcription/translation system
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US Patent 7659391 Method for the in vitro synthesis of short double stranded RNAs
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US Patent 7794939 Methods of DNA methylation detection
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US Patent 7807407 Detection of truncation mutations by mass spectrometry
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US Patent 7820427 Microfluidic device and methods of using same
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US Patent 8357529 Methods of in vitro protein synthesis
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US Patent 8557518 Microfluidic and nanofluidic devices, systems, and applications
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US Patent 8580494 Methods and compositions for amplification and detection of MicroRNAs
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US Patent 8859229 Transient transfection with RNA
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US Patent 8945861 Methods for isotopically labeling biomolecules using mammalian cell-free extracts
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US Patent 9090928 Site-specific incorporation of phosphoserine into proteins in
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US Patent 9206216 Modified nucleotides methods and kits
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US Patent 9249423 Method of de-differentiating and re-differentiating somatic cells using RNA
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US Patent 9410148 Method for constructing libraries of non-standard peptide compounds comprising N-methyl amino acids and other special (non-standard) amino acids and method for searching and identifying active species
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US Patent 9506845 Methods, systems and devices for multiple single-cell capturing and processing using microfluidics
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US Patent 9574167 Methods and apparatus for independent control of product and reactant concentrations
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US Patent 9637739 RNA-directed DNA cleavage by the Cas9-crRNA complex
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US Patent 9701993 Artificial translation/synthesis system
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US Patent 9738908 CRISPR/Cas systems for genomic modification and gene modulation
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US Patent 9951349 Compositions and methods for transient expression of recombinant RNA
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US Patent 10113168 Ribozyme with tRNA synthetase activity and methods of manufacturing and using the same
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US Patent 6942865 Methods and reagents to detect and characterize norwalk and related viruses
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US Patent 6951725 In vitro protein interaction detection systems
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US Patent 6955876 Compositions and systems for identifying and comparing expressed genes (mRNAs) in eukaryotic organisms
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US Patent 6977150 Process and compositions for peptide, protein and peptidomimetic synthesis
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US Patent 7011958 Method for improving the stability of linear DNA in cell-free in vitro transcription/translation systems
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US Patent 7063946 Methods, reagents, kits and apparatus for protein function analysis
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Patent Primary Examiner
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Jennifer Wecker
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CPC Code
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C12N 15/101
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C12M 41/48
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G01N 21/01
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G01N 2021/0187
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B01L 3/502769
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B01L 3/502707
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B01L 2400/0487
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A61P 35/00
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