US Patent 11959108 Engineered protease variants
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US Patent 11959108 Engineered protease variants
Article
Patent abstract
The present invention provides engineered protease polypeptides and compositions thereof. The engineered protease polypeptides have been optimized to provide improved activity, improved thermostability, protease stability, autolytic stability, and stability under a range of pH conditions, including acidic (pH<7) and basic (pH>7) conditions. The invention also relates to the use of the compositions comprising the engineered protease polypeptides for therapeutic and/or nutritional purposes. The present invention also provides polynucleotides encoding the engineered protease polypeptides, as well as methods for making the engineered polynucleotides and protease polypeptides.
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Patent Inventor Names
Chinping Chng0
Kerryn McCluskie0
Kristen Jean Vallieu0
Moulay Hicham Alaoui Ismaili0
Nikki Dellas0
Ravi David Garcia0
Date of Patent
April 16, 2024
0Patent Application Number
174601410
Date Filed
August 27, 2021
0Patent Citations
Patent Primary Examiner
CPC Code
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