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US Patent 11970524 Recombinant ROBO2 proteins, compositions, methods and uses thereof

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Is a

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Janet Elizabeth Buhlmann0

Zong Sean Juo0

David J. Salant0

Matthew Russo0

Nathan Higginson-Scott0

Stefano V. Gulla0

Xueping Fan0

Michael Shamashkin0

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Date of Patent

April 30, 2024

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Patent Application Number

171259030

Date Filed

December 17, 2020

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Patent Citations

US Patent 9493529 Robo1-Fc fusion protein and use thereof for treating tumours

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US Patent 10358677 Method for treating kidney disease with a SLIT2-binding extracellular domain of ROBO2

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US Patent 7939497 Detection and modulation of slit and roundabount (robo) mediated angiogenesis and uses thereof

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US Patent 9572879 ROBO2 inhibitory compositions comprising SLIT2-binding extracellular domain of ROBO2

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Patent Primary Examiner

Zachary C Howard

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CPC Code

0

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Patent abstract

The invention provides recombinant Roundabout Receptor 2 (ROBO2) proteins designed to bind SLIT ligands and prevent their binding to ROBO2 cell surface receptors. Also provided are methods for use of these recombinant ROBO2 proteins.

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