US Patent 11987579 Niclosamide analogues and therapeutic use thereof
Patent 11987579 was granted and assigned to Duke University on May, 2024 by the United States Patent and Trademark Office.
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US Patent 11987579 Niclosamide analogues and therapeutic use thereof
Article
Patent abstract
Described are niclosamide analogue compounds, pharmaceutical compositions thereof, and method of using the corner pounds and compositions for treating a disease associated with dysregulation of the Wnt/Frizzled signaling pathway, such as cancer, fatty liver, antibiotic resistance, and viral infection. The disclosed compounds and compositions may also be used for modulating mitochondrial function and for treating certain non-cancer diseases and/or diorders, such as diabetes, fibrotic disease, primary sclerosing cholangitis.
Infobox
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Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Herbert Kim Lyerly0
Jiangbo Wang0
Robert A. Mook0
Wei Chen0
Xiu-Rong Ren0
Date of Patent
May 21, 2024
0Patent Application Number
172637690
Date Filed
July 30, 2019
0Patent Citations
Patent Primary Examiner
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