Patent 11992531 was granted and assigned to C4 Therapeutics on May, 2024 by the United States Patent and Trademark Office.
This invention provides Degronimers that have carbon-linked E3 Ubiquitin Ligase targeting moieties (Degrons), which can be linked to a targeting ligand for a protein that has been selected for in vivo degradation, and methods of use and compositions thereof as well as methods for their preparation.