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US Patent 11993637 Modified FGF-21 polypeptides with non-naturally encoded amino acids
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Edits on 30 May, 2024
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US Patent 11993637 Modified FGF-21 polypeptides with non-naturally encoded amino acids
Article
Patent abstract
Modified FGF-21 polypeptides and uses thereof are provided.
Infobox
Is a
Patent
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Patent Applicant
AMBRX INC
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Patent Jurisdiction
United States Patent and Trademark Office
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Patent Number
11993637
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Patent Inventor Names
Anna-Maria A. Hays Putnam
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Jason Pinkstaff
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Lillian Skidmore
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Nick Knudsen
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Roberto Mariani
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Thomas P. Cujec
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Vadim Kraynov
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William M. Keefe
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Date of Patent
May 28, 2024
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Patent Application Number
17165351
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Date Filed
February 2, 2021
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Patent Citations
US Patent 7259248 Human FGF-21 polypeptides
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US Patent 7408047 Fibroblast growth factor-like polypeptides
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US Patent 7459540 Fibroblast growth factor-like polypeptides
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US Patent 7576190 FGF-21 fusion proteins
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US Patent 7582607 Muteins of fibroblast growth factor 21
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US Patent 7622445 Muteins of fibroblast growth factor 21
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US Patent 7655627 Muteins of fibroblast growth factor 21
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US Patent 7667008 Fibroblast growth factor-like polypeptides and variants thereof
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US Patent 7816320 Formulations of human growth hormone comprising a non-naturally encoded amino acid at position 35
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US Patent 7846445 Methods for production of unstructured recombinant polymers and uses thereof
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US Patent 8012931 Modified FGF-21 polypeptides and their uses
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US Patent 8361963 Uses of FGF21 polypeptides comprising two or more mutations
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US Patent 8383365 Methods of making FGF-21 mutants comprising non-naturally encoded phenylalanine derivatives
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US Patent 8410051 FGF21 mutants and uses thereof
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US Patent 9006400 Fibroblast growth factor-21-Fc fusion proteins
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US Patent 9023791 Fibroblast growth factor 21 mutations
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US Patent 9079971 Modified FGF-21 polypeptides comprising non-naturally occurring amino acids
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US Patent 9434778 Modified FGF-21 polypeptides comprising an internal deletion and uses thereof
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US Patent 9493530 FGF21 mutants comprising a mutation at position 98, 171 and/or 180
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US Patent 9517273 Methods of treatment using modified FGF-21 polypeptides comprising non-naturally occurring amino acids
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US Patent 9631004 Modified FGF-21 polypeptides comprising an internal deletion and uses thereof
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US Patent 9975936 Nucleic acids encoding modified FGF-21 polypeptides comprising non-naturally occurring amino acids
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US Patent 10189883 Therapeutic uses of modified FGF-21 polypeptides
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US Patent 10377806 Methods of treating diseases associated with fibrosis using modified FGF-21 polypeptides and uses thereof
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US Patent 6852502 Electrochemiluminescent enzyme biosensors
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US Patent 6927042 Glycoprotein synthesis
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US Patent 7045337 In vivo incorporation of unnatural amino acids
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US Patent 7083970 Methods and compositions for the production of orthogonal tRNA-aminoacyl tRNA synthetase pairs
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Patent Primary Examiner
Elly-Gerald Stoica
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CPC Code
C12N 15/70
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C07K 14/50
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A61K 47/60
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A61K 38/00
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A61K 38/1825
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