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US Patent 12004495 Genetically modified non-human animals with humanized immunoglobulin locus

OverviewStructured DataIssuesContributorsActivity
Is a
Patent
Patent
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Date Filed
September 2, 2020
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Date of Patent
June 11, 2024
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Patent Application Number
17010587
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Patent Citations
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US Patent 8791323 Hybrid antibodies comprising human variable regions and mouse constant regions produced in a genetically modified mouse
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US Patent 10194645 Mouse λ light chain locus
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US Patent 10226033 Animal models and therapeutic molecules
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US Patent 10227625 Methods of modifying eukaryotic cells
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US Patent 10251377 Transgenic non-human vertebrate for the expression of class-switched, fully human, antibodies
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US Patent 10344299 Compositions and methods for modifying cells
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US Patent 10378037 Methods of making a nucleic acid encoding a human variable region
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US Patent 10378038 Mice that produce hybrid antibodies
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US Patent 10378039 Mouse embryonic stem cells comprising a hybrid heavy chain immunoglobulin locus
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US Patent 10378040 Mice that produce hybrid antibodies
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•••
Patent Inventor Names
Shuwen Huang
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Huizhen Zhao
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Yabo Zhang
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Lili Liu
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Yuelei Shen
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Hui Lu
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Jiawei Yao
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
12004495
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Patent Primary Examiner
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Allison M Fox
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