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Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Tania Benatar0
Christopher W. Helsen0
Andreas Bader0
Philbert Ip0
Ling Wang0
Date of Patent
June 25, 2024
0Patent Application Number
182463180
Date Filed
June 1, 2022
0Patent Citations
...
Patent Primary Examiner
Patent abstract
Claudin 18.2 T cell antigen couplers (TACs) polypeptides having (i) an antigen-binding domain that binds Claudin 18.2, (ii) an antigen-binding domain that binds a protein associated with a TCR complex, and (iii) a T cell receptor signaling domain polypeptide are provided. Nucleic acids encoding the claudin 18/2 TACs are also provided.
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