Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Christopher W. Helsen0
Jonathan Bramson0
Kenneth Anthony Mwawasi0
Rajanish Giri0
Galina Denisova0
Date of Patent
October 8, 2019
0Patent Application Number
151171730
Date Filed
February 6, 2015
0Patent Citations Received
...
Patent Primary Examiner
Patent abstract
A trifunctional molecule comprising a target-specific ligand, a ligand that binds a protein associated with the TCR complex and a T cell receptor signaling domain polypeptide is provided. Engineering T cells with this novel receptor engenders antigen specific activation of numerous T cell functions, including cytokine production, degranulation and cytolysis.
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