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US Patent 12024517 Salts of an FGFR inhibitor

Patent 12024517 was granted and assigned to Incyte on July, 2024 by the United States Patent and Trademark Office.

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 US Patent 12024517 Salts of an FGFR inhibitor

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Patent abstract

The present invention relates to salt forms of the Fibroblast Growth Factor Receptors (FGFR) inhibitor 3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-(morpholin-4-ylmethyl)-1,3,4,7-tetrahydro-2H-pyrrolo[3′,2′:5,6]pyrido[4,3-d]pyrimidin-2-one, including methods of preparation thereof, where the compound is useful in the treatment of FGFR mediated diseases such as cancer.

Infobox
Is a
Patent
Patent
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Patent Applicant
Incyte
Incyte
0
Current Assignee
Incyte
Incyte
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
120245170
Patent Inventor Names
Jiacheng Zhou0
Qun Li0
Zhongjiang Jia0
Date of Patent
July 2, 2024
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Patent Application Number
175035130
Date Filed
October 18, 2021
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Patent Citations
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US Patent 7125880 Corticotropin releasing factor antagonists
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US Patent 9388185 Substituted pyrrolo[2,3-b]pyrazines as FGFR inhibitors
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US Patent 9440976 1,7-diazacarbazoles and methods of use
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US Patent 9533954 Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3
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US Patent 9580423 Bicyclic heterocycles as FGFR4 inhibitors
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US Patent 9611267 Substituted tricyclic compounds as FGFR inhibitors
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US Patent 9708318 Bicyclic heterocycles as FGFR4 inhibitors
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US Patent 9745311 Substituted pyrrolo[2,3-b]pyrazines as FGFR inhibitors
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US Patent 9801889 Bicyclic heterocycles as FGFR4 inhibitors
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US Patent 9890156 Bicyclic heterocycles as FGFR4 inhibitors
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US Patent 10016348 Two-phase composition comprising a fatty acid ester of sugar or a liquid alkyl polyglucoside, with an HLB < 8, and a C
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US Patent 10040790 Bicyclic heterocycles as FGFR inhibitors
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US Patent 10131667 Substituted tricyclic compounds as FGFR inhibitors
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US Patent 10208024 2-aryl- and 2-heteroaryl-substituted 2-pyridazin-3(2H)-one compounds as inhibitors of FGFR tyrosine kinases
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US Patent 10213427 Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3
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US Patent 10214528 Bicyclic heterocycles as FGFR4 inhibitors
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US Patent 10251892 Bicyclic heterocycles as FGFR4 inhibitors
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US Patent 10308644 Heterocyclic compounds as immunomodulators
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US Patent 10350240 Lanthanum carbonate hydroxide, lanthanum oxycarbonate and methods of their manufacture and use
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US Patent 10357431 Process for the preparation of a pharmaceutical composition comprising a low soluble pharmaceutically active ingredient
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US Patent 10450313 Bicyclic heterocycles as FGFR inhibitors
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US Patent 10611762 Crystalline forms of a FGFR inhibitor and processes for preparing the same
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US Patent 10632126 Bicyclic heterocycles as FGFR4 inhibitors
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US Patent 10738048 Bicyclic heterocycles as FGFR4 inhibitors
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US Patent 10813930 Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3
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US Patent 10851105 Bicyclic heterocycles as FGFR4 inhibitors
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US Patent 10947230 Bicyclic heterocycles as FGFR inhibitors
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US Patent 11014923 Bicyclic heterocycles as FGFR4 inhibitors
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US Patent 11053246 Substituted tricyclic compounds as FGFR inhibitors
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US Patent 11407750 Derivatives of an FGFR inhibitor
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US Patent 11466004 Solid forms of an FGFR inhibitor and processes for preparing the same
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US Patent 11472801 Crystalline forms of a FGFR inhibitor and processes for preparing the same
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US Patent 11530214 Bicyclic heterocycles as FGFR inhibitors
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US Patent 11628162 Methods of treating cancer with an FGFR inhibitor
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US Patent 11667635 Bicyclic heterocycles as FGFR4 inhibitors
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US Patent 6998408 6-5, 6-6, or 6-7 Heterobicycles as factor Xa inhibitors
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US Patent 7074801 Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof
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Patent Primary Examiner
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Rebecca L Anderson
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CPC Code
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C07D 471/14
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