Golden has been acquired by ComplyAdvantage.Read about it here ⟶

‌

US Patent 12065467 High-transduction-efficiency rAAV vectors, compositions, and methods of use

Overview Structured Data Issues Contributors Activity

Is a

0

Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

0

Patent Number

Patent Inventor Names

Mavis Agbandje-McKenna0

Kim M. Van Vliet0

Arun Srivastava0

George Vladimirovich Aslanidi0

Date of Patent

August 20, 2024

0

Patent Application Number

178107290

Date Filed

July 5, 2022

0

Patent Citations

US Patent 8802440 Therapeutic methods based on tyrosine-substituted, capsid-modified rAAV vectors

0

US Patent 9157098 Transduction efficiency, capsid-modified rAAV vectors and methods of use

0

US Patent 9611302 High-transduction-efficiency RAAV vectors, compositions, and methods of use

0

US Patent 9725485 AAV vectors with high transduction efficiency and uses thereof for gene therapy

0

US Patent 9775918 Capsid-modified rAAV vectors and methods of use

0

US Patent 9920097 Capsid-modified rAAV vector compositions having improved transduction efficiencies, and methods of use

0

US Patent 10011640 Capsid-modified rAAV vector compositions and methods therefor

0

US Patent 10294281 High-transduction-efficiency rAAV vectors, compositions, and methods of use

0

...

Patent Primary Examiner

M Franco G Salvoza

0

Patent abstract

The present invention provides AAV capsid proteins comprising modification of one or a combination of the surface-exposed lysine, serine, threonine and/or tyrosine residues in the VP3 region. Also provided are rAAV virions comprising the AAV capsid proteins of the present invention, as well as nucleic acid molecules and rAAV vectors encoding the AAV capsid proteins of the present invention. Advantageously, the rAAV vectors and virions of the present invention have improved efficiency in transduction of a variety of cells, tissues and organs of interest, when compared to wild-type rAAV vectors and virions.

Timeline

No Timeline data yet.

Further Resources

Title

Author

Link

Type

Date

No Further Resources data yet.

References

Find more entities like US Patent 12065467 High-transduction-efficiency rAAV vectors, compositions, and methods of use

Use the Golden Query Tool to find similar entities by any field in the Knowledge Graph, including industry, location, and more.

Open Query Tool

Golden Query Tool