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US Patent 12071470 Human immunodeficiency virus neutralizing antibodies and methods of use thereof

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Ron Diskin0

Johannes Scheid0

Pamela J. Bjorkman0

Michel Nussenzweig0

Date of Patent

August 27, 2024

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Patent Application Number

181728360

Date Filed

February 22, 2023

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Patent Citations

US Patent 9783594 Human immunodeficiency virus neutralizing antibodies and methods of use thereof

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US Patent 9890207 Highly active agonistic CD4 binding site anti-HIV antibodies (HAADS) comprising modified CDRH2 regions that improve contact with GP120

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US Patent 10035844 Broadly neutralizing HIV-1 VRC07 antibodies that bind to the CD4-binding site of the envelope protein

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US Patent 10676521 Combination of broadly neutralizing HIV antibodies and viral inducers

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US Patent 7585961 Nucleic acid encoding human antibodies specific for interleukin 15 (IL-15)

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US Patent 7763247 Humanized collagen antibodies and related methods

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US Patent 9493549 Antibodies directed toward the HIV-1 GP120 CD4 binding site with increased potency and breadth

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US Patent 9695230 Broadly neutralizing HIV-1 VRC07 antibodies that bind to the CD4-binding site of the envelope protein

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Patent Primary Examiner

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Patent abstract

The invention provides broadly neutralizing antibodies directed to epitopes of Human Immunodeficiency Virus, or HIV. The invention further provides compositions containing HIV antibodies used for prophylaxis, and methods for diagnosis and treatment of HIV infection.

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