Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Yanjie Bao0
Jerel Vega0
Padmanabh Chivukula0
Samantha Murphy0
Rajesh Mukthavaram0
Priya Karmali0
Christine Esau0
Date of Patent
September 10, 2024
0Patent Application Number
170428480
Date Filed
April 1, 2019
0Patent Citations
...
Patent Primary Examiner
Patent abstract
Nucleic acid immunization is achieved by delivering a nucleic acid (NA), e.g., a mRNA or a DNA, encapsulated within a lipid-NA nanoparticle. The NA encodes an immunogenic compound of interest. The lipid-NA nanoparticle is effective for in vivo delivery of NA to a vertebrate cell, including upon administration to a subject. The lipid-NA nanoparticle are incorporated in pharmaceutical compositions for immunizing subjects against various diseases.
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