Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Christopher A. Reid0
Date of Patent
October 1, 2024
0Patent Application Number
184936630
Date Filed
October 24, 2023
0Patent Citations
...
Patent Primary Examiner
Patent abstract
The present disclosure provides recombinant adeno-associated virus (rAAV) virions with an engineered capsid protein identified using a high-throughput sequencing screen or rational design. In particular, the disclosure provides AAV5 virions and capsid proteins with increased transduction efficiency in cardiac cells, increased cell-type selectivity, and/or other desirable properties.
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